翻訳と辞書
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・ SP-85 (Brazil)
・ SP-88
・ SP-91
・ SP-92
・ SP-95
・ SP-97
・ SP-98
・ SP-A
・ SP-DEVS
・ Sp.
・ SP.A-Spirit
・ SP/300.R
・ SP/k
・ Sp/KLF family
・ SP1
Sp1 transcription factor
・ Sp100 nuclear antigen
・ SP101
・ SP103
・ SP110
・ SP2
・ Sp2 transcription factor
・ SP21
・ SP23
・ SP29
・ SP3
・ Sp3 transcription factor
・ SP303
・ SP350
・ SP4


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Sp1 transcription factor : ウィキペディア英語版
Sp1 transcription factor

Transcription factor Sp1, also known as specificity protein 1
* is a protein that in humans is encoded by the SP1 gene.
== Function ==

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor.〔
In the SV40 virus, Sp1 binds to the GC boxes in the regulatory region (RR) of the genome.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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